Arizona Cardinals vs. San Francisco 49ers Preview and Predictions

Aaron Nagler@Aaron_NaglerNFL National Lead WriterDecember 24, 2012

The San Francisco 49ers got a dose of reality against the Seattle Seahawks at CenturyLink Field on Sunday and will look to get back on track this week against divisional rival Arizona Cardinals. 

The Cardinals will be playing out the finale of an extremely disappointing 2012 season that ends as it began: with a cloud surrounding the quarterback position. Head coach Ken Wisenhunt spent all year trying to find a viable signal-caller and failed at every turn, and it could very well end up costing him his job. 

For the 49ers, Colin Kaepernick and the offense need to get back to basics, namely handing the ball off to Frank Gore. San Francisco got far too cute early against the Seahawks, and it cost the team. Head coach and play-caller Jim Harbaugh needs to get back to what made this team so successful in 2011 and earlier this year by feeding the running game, especially Frank Gore. 

In the video above, we look at the biggest storyline surrounding the game and give our picks. Let us know in the comments below where you agree and disagree, and let us know who you think wins the game.